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The seat, which flips from Republican to Democrat, was vacated by retiring GOP Sen. Pat Toomey.
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Shootings in Pennsylvania, South Carolina, Tennessee and Arizona were among the incidents across eight states over the weekend.
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This month's primaries and runoffs will serve as a test of the power of former President Donald Trump's endorsements up and down the ballot.
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In cases from North Carolina and Pennsylvania, Republican state legislatures sought to block decisions issued by state supreme courts based on the states' respective constitutions.
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Officials said 10 people suffered minor injuries and at least three were taken to the hospital after the collapse, which appears to have involved several vehicles and a Port Authority bus.
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The lawsuit argued a 2019 state law authorizing universal mail-in voting was unconstitutional and that all ballots cast by mail in the general election in Pennsylvania should be thrown out.
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Two young, female first-time candidates won primary races against established incumbent Democrats from a family with deep roots in southwestern Pennsylvania.