In Robin Dando's lab, several mice chowed down on a specialized diet designed to make them as fat as possible. "I can say the mice are happy. They love this unhealthy diet, and pretty fast they get pretty overweight," says Dando, an assistant professor of food science at Cornell University.
But the mice were not long for this world. Eight weeks after they started their delicious nosh, they were euthanized and their tongues were excised for direct comparison against their skinnier brethren.