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President-elect Joe Biden could be the first Democrat since 1885 to enter office without his party controlling both houses of Congress. That creates challenges for his ambitious agenda.

NPR's Mary Louise Kelly speaks with Kentucky state Rep. Attica Scott about the indictment of the former Louisville police officer in the shooting death of Breonna Taylor.

NPR's Noel King talks to California Secretary of State Alex Padilla about what the state has done since officials received reports about possible unauthorized ballot boxes in several counties.

The U.S. is rejoining the world's largest effort to address climate change: the 2015 Paris climate agreement. Climate change is one of the Biden administration's top priorities.

NPR looks at President Biden's first full week in office. From executive orders to big legislative proposals, his presidential leadership already contrasts starkly with his predecessor's.

Rhode Island Gov. Gina Raimondo, expected to oversee the U.S. Census Bureau as the next commerce secretary, says she will "rely on the experts" at the agency to ensure the 2020 census is accurate.

Los Angeles voters elected a progressive reformer to be county district attorney. George Gascón has moved quickly to upend how the nation's largest local prosecutor's office administers justice.

Boston set a goal of eliminating chronic homelessness by the end of 2018. The goal will not be reached. The city has made big progress in housing people who are homeless, but major barriers remain.

The lead lawyer for the National Security Council is John Eisenberg, who received concerns about President Trump's call with Ukraine's president. What more do we know about him?

NPR's Ailsa Chang speaks with Republican Congressman Garret Graves of Louisiana about President Biden's meeting with a bipartisan group of members of Congress about his infrastructure proposal.

The legislation would address the spike in hate crimes and violence targeted at the Asian American and Pacific Islander community. Democrats need GOP votes to advance the bill in the Senate this week.

On the fourth day of Derek Chauvin's trial for the murder of George Floyd, the courtroom's focus shifted to Floyd's drug use and medical evidence.

The president opened a climate summit by announcing that the United States will aim to cut its greenhouse gas emissions in half, based on 2005 levels, by the end of the decade.

NPR's Audie Cornish speaks with Los Angeles Times staff writer Stacy Perman about reforms the Hollywood Foreign Press Association will vote on Thursday under pressure from top Hollywood publicists.

NPR's Ari Shapiro speaks with George Clinton about the legacy of his work, how the spirit of funk is synonymous with freedom and an artist he's grateful for: Constance Hauman.

Sen. Shelley Moore Capito, R-W.V., said that President Biden ended negotiations with Republicans on an infrastructure deal Tuesday, abandoning talks over one of his top priorities.

Scott Rivkees announced he will leave his post as surgeon general and secretary of the Florida Department of Health next month. But the move comes amid a surge of COVID-19 cases and deaths. Combine that with Gov. Ron DeSantis’ antagonism to federal health authorities and mask mandates, and it might make it difficult to find a replacement.

The U.S. Open gets underway in Flushing Meadows, New York, Monday. For a preview, Steve Inskeep talks to Jon Wertheim of Sports Illustrated. Roger Federer is the favorite on the men's side while Serena Williams is the overwhelming favorite for the women.

NPR's Scott Simon talks with Annie Lowrey of the Atlantic about what she calls the Great Affordability Crisis. She says the cost of housing and health care is bleeding some American families dry.

In only their second call since Biden took office, the two leaders spoke about "the responsibility of both nations to ensure competition does not veer into conflict," according to the White House.